$2,500,000 was the original top prize in the Pilot version of Deal or No Deal and a special top prize on the primetime version of Deal or No Deal US, and the top prize in both versions of Yoo si Vooy. It was also the 2nd highest amount in the primetime version when the top prize was $5,000,000. It has similar graphics to $1,000,000 when it's the 2nd highest amount and has the same graphics as the other Progressive Prize amounts and the MDM when it's the top prize.
Mike picked case #9 as his personal case which contained the $2,500,000 in 2004. He didn't win it as he took a deal and sold his case for $416,000, making it the worst deal ever (Prior to Matty's case having $3,000,000) (A difference of -$2,084,000, would have taken his final offer to $1,251,000.)
Becky picked the $2,500,000 in case #13 on 2006-03-02.
Casey picked the $2,500,000 in case #3 on 2006-06-05.
Jeff picked the $2,500,000 in case #18 after taking a deal of $177,000.